Brand
name: Provera (Medroxyprogesterone)
Pronounced: DE-po pro-VEH-ra
Generic name: Medroxyprogesterone acetate
Why is Provera (Medroxyprogesterone) prescribed?
Provera (Medroxyprogesterone) Contraceptive Injection is given in the buttock or upper
arm to prevent pregnancy. It is more than 99 percent effective; your
chances of becoming pregnant during the first year of use are less
than 1 in 100. The injection is given every 3 months (13 weeks) by
your doctor. Provera (Medroxyprogesterone) works by preventing the release of hormones
called gonadotropins from the pituitary gland in the brain. Without
these hormones, the monthly release of an egg from the ovary cannot
occur. If no egg is released, pregnancy is impossible. Provera (Medroxyprogesterone)
also causes changes in the lining of the uterus that make pregnancy
less likely even if an egg is released.
In higher doses, Provera (Medroxyprogesterone) is also used in the treatment of certain
cancers including cancer of the endometrium (lining of the uterus)
and kidney cancer.
Most important fact about Provera (Medroxyprogesterone) without prescriptions/Where
to order online.
Because Provera (Medroxyprogesterone) is a long-acting form of birth control, it will
take a while for the effects of your last injection to wear off. In
medical studies, only 68 percent of women became pregnant within 12
months after stopping Provera (Medroxyprogesterone). However, within 18 months, 93 percent
had become pregnant. If you think you will want to get pregnant shortly
after you stop using birth control, Provera (Medroxyprogesterone) may not be the ideal
method for you. The amount of time you use Provera (Medroxyprogesterone) does not affect
the delay in becoming pregnant when you stop.
How should you take Provera (Medroxyprogesterone)?
Provera (Medroxyprogesterone) is given by a doctor. To make sure you are not pregnant
when you receive your first injection, it is given only during the
first 5 days after your menstrual period, when it is very unlikely
that you could be pregnant. If you are breastfeeding, Provera (Medroxyprogesterone)
is given 6 weeks after childbirth to reduce the infant's exposure to
the drug through breast milk. If you are not breastfeeding, it is given
within 5 days of childbirth.
Provera (Medroxyprogesterone) must be taken every 3 months (13 weeks), on schedule.
Although the birth-control effects of the drug generally take time
to wear off, there is still a possibility of becoming pregnant right
away if you miss your scheduled injection.
If you miss a Provera (Medroxyprogesterone) dose:
If you allow more than 13 weeks to elapse before your next injection,
your doctor will do a test to make sure you are not pregnant before
giving you another injection.
Storage instructions...
Provera (Medroxyprogesterone) is always given at a doctor's office or clinic, never
at home.
Provera (Medroxyprogesterone) side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking Provera (Medroxyprogesterone).
By far, the most common side effect of Provera (Medroxyprogesterone) is unpredictable
menstrual bleeding. In fact, most women have some change in their menstrual
pattern. For example, when first taking Provera (Medroxyprogesterone), it is common
to have spotting between menstrual periods, or an increase or decrease
in the amount of bleeding when menstrual periods occur. With continued
use, many women stop having their menstrual periods altogether.
By 12 months (or four injections), 55 percent of women report not
having periods, and by 24 months, 68 percent no longer have periods.
Going without a menstrual period is not an indication that something
is wrong, however.
* Side effects may include:
Abdominal pain or discomfort, dizziness, headache, nervousness, unpredictable
menstrual bleeding, weakness or fatigue, weight gain or loss
Why should Provera (Medroxyprogesterone) not be prescribed?
You should not use Provera (Medroxyprogesterone) if you know or suspect you are pregnant,
or if you have unusual vaginal bleeding that has not been diagnosed
by a doctor.
Also avoid Provera (Medroxyprogesterone) if you know or suspect you have breast cancer,
or if you have liver disease.
Do not use this method of birth control if you have thrombophlebitis
(inflammation of a vein with development of a blood clot), or have
ever had any blood-clotting disorders, such as a stroke, or disease
of the blood vessels in the brain.
You should not take Provera (Medroxyprogesterone) if you have ever had an allergic
reaction to it or to any of its ingredients.
Special warnings about Provera (Medroxyprogesterone)
Call your doctor immediately if any of these problems occur after
an injection of Provera (Medroxyprogesterone): sharp chest pain, coughing of blood,
sudden shortness of breath, sudden severe headache or vomiting, dizziness
or fainting, problems with your eyesight or speech, weakness or numbness
in an arm or leg, severe pain or swelling in the calf, unusually heavy
vaginal bleeding, severe pain or tenderness in the lower abdominal
area, migraine headache, or persistent pain, pus, or bleeding at the
injection site.
Studies indicate that using Provera (Medroxyprogesterone) may make you more prone to
osteoporosis, or brittle bone disease. The rate at which bone loss
occurs is greatest during the early years of Provera (Medroxyprogesterone) use, and
the risk decreases to normal over time.
Studies of women who have used Provera (Medroxyprogesterone) for a long time have found
virtually no increased risk of cancers of the breast, ovaries, liver,
or cervix (mouth of the uterus). Some studies do show a slight increased
risk of breast cancer in women younger than 35 years old who have taken
Provera (Medroxyprogesterone) for a short time, but the increase is about three additional
cases of breast cancer per 10,000 women. At the same time, Provera (Medroxyprogesterone)
helps reduce the chance of cancer of the endometrium, or lining of
the uterus.
Provera (Medroxyprogesterone) may cause fluid retention, so if you have conditions
that may be worsened by fluid retention, such as epilepsy, migraine
headaches, asthma, heart disease, or kidney disease, make sure the
doctor is aware of it.
Provera (Medroxyprogesterone) tends to alter levels of blood sugar, so diabetic women
need to be carefully observed by their doctors when taking Provera (Medroxyprogesterone).
If you develop jaundice (a yellowing of the skin and whites of the
eyes caused by liver disease), you probably should not receive Provera (Medroxyprogesterone)
again.
Most women gain weight while they are using Provera (Medroxyprogesterone).
While it is an excellent birth control method, Provera (Medroxyprogesterone) does not
protect you against AIDS or other sexually transmitted diseases. If
you are concerned about AIDS or other STDs, be sure your partner uses
a condom during intercourse (or, for absolute safety, abstain from
sex).
Before you start using Provera (Medroxyprogesterone), be sure to tell your doctor if
you or anyone in your family has ever had breast cancer; if you have
ever had any problems with your breasts; if your menstrual periods
have ever been irregular or spotty; if you have kidney disease, high
blood pressure, migraine headaches, asthma, epilepsy, or a history
of depression; if you or anyone in your family has or has had diabetes;
or if you are taking any prescription or over-the-counter drugs.
Possible food and drug interactions when taking Provera (Medroxyprogesterone)
If Provera (Medroxyprogesterone) is taken with aminoglutethimide (Cytadren), a drug
used to treat a disorder of the adrenal glands called Cushing's syndrome,
it could make the Provera (Medroxyprogesterone) less potent, which could lead to unexpected
pregnancy. Check with your doctor before taking Cytadren if you are
on Provera (Medroxyprogesterone).
Special information if you are pregnant or breastfeeding
Provera (Medroxyprogesterone) is not given to pregnant women. If an unexpected pregnancy
occurs 1 to 2 months after a Provera (Medroxyprogesterone) injection, the baby is more
likely to have a low birth weight or other health problems; birth defects
are possible if you use the drug during the first 3 months of pregnancy.
Children born to women who were taking Provera (Medroxyprogesterone) show no signs of
poor health or development. Because Provera (Medroxyprogesterone) does not prevent the
breasts from producing milk, it can be used by women who are breastfeeding.
However, to minimize the amount of Provera (Medroxyprogesterone) that is passed to the
infant during the first weeks of life, the drug is not given until
6 weeks after childbirth. Studies show Provera (Medroxyprogesterone) is not harmful
to the infant then or later in life.
Recommended dosage for Provera (Medroxyprogesterone)
Provera (Medroxyprogesterone) is given as a single 150-milligram injection every 3
months (13 weeks).
Overdosage
An overdose of Provera (Medroxyprogesterone) is highly unlikely, since it is given
as a single injection by your doctor. However, if you suspect you have
received an overdose, seek medical attention immediately.
Why is Provera prescribed?
Provera is derived from the female hormone progesterone. You may be
given Provera if your menstrual periods have stopped or a female hormone
imbalance is causing your uterus to bleed abnormally. Provera is also
prescribed to prevent abnormal growth of the uterine lining in women
taking estrogen replacement therapy.
Other forms of medroxyprogesterone, such as Provera (Medroxyprogesterone), are used
as a contraceptive injection and prescribed in the treatment of endometrial
cancer.
Some doctors prescribe Provera to treat endometriosis, menopausal
symptoms, premenstrual tension, sexual aggressive behavior in men,
and sleep apnea (temporary failure to breath while sleeping).
Most important fact about Provera
You should never take Provera during the first 4 months of pregnancy.
During this formative period, even a few days of treatment with Provera
might put your unborn baby at increased risk for birth defects. If
you take Provera and later discover that you were pregnant when you
took it, discuss this with your doctor right away.
How should you take Provera Free RX?
Provera may be taken with or between meals.
Do not change from one brand to another without consulting your doctor
or pharmacist.
If you miss a dose...
Take it as soon as you remember. If it is almost time for your next
dose, skip the one you missed and go back to your regular schedule.
Never take 2 doses at the same time.
Storage instructions...
Store at room temperature.
Provera side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking Provera.
* Side effects may include:
Acne, anaphylaxis (life-threatening allergic reaction), blood clot in a vein,
lungs, or brain, breakthrough bleeding (between menstrual periods), breast
tenderness or sudden or excessive flow of milk, cervical erosion or changes
in secretions, depression, excessive growth of hair, fever, fluid retention,
hair loss, headache, hives, insomnia, itching, lack of menstruation, menstrual
flow changes, spotting, nausea, rash, skin discoloration, sleepiness, weight
gain or loss, yellowed eyes and skin
Why should Provera not be prescribed?
Provera should never be taken during pregnancy. Avoid it if you even
suspect you're pregnant. Doctors once prescribed Provera as a test
for pregnancy, but no longer do so for 2 reasons:
* Quicker, safer pregnancy tests are now available.
* If you are in fact pregnant, Provera might injure the baby.
Similarly, Provera used to be given to try to prevent miscarriage.
However, doctors now believe that this treatment is not only ineffective
but also potentially harmful to the baby.
Do not take Provera if you have:
* Cancer of the breast or genital organs
* Liver disease or a liver condition
* A dead fetus still in the uterus
* Undiagnosed bleeding from the vagina
Do not take Provera if you have, or have ever developed, blood clots.
Avoid it, too, if it gives you an allergic reaction.
Special warnings about Provera
Before you start to take Provera, your doctor will give you a complete
physical exam, including examination of your breasts and pelvic organs.
You should also have a cervical smear (Pap test).
Provera may cause some degree of fluid retention. If you have a medical
condition that could be made worse by fluid retention--such as epilepsy,
migraine, asthma, or a heart or kidney problem--make sure your doctor
knows about it.
Provera may mask the onset of menopause. In other words, while taking
Provera you may continue to experience regular menstrual bleeding even
if your menopause has started.
Provera may make you depressed, especially if you have suffered from
depression in the past. If you become seriously depressed, tell your
doctor; you should probably stop taking Provera.
If you are diabetic, Provera could make your diabetes worse; your
doctor will want to watch you closely while you are taking this drug.
There is some concern that Provera, like birth control pills, may
increase your risk for a blood clot in a vein. If you experience any
symptoms that might suggest the onset of such a condition--pain with
swelling, warmth, and redness in a leg vein, coughing or shortness
of breath, vision problems, migraine, or weakness or numbness in an
arm or leg--see your doctor immediately.
Tell your doctor right away if you lose some or all of your vision
or you start seeing double. You may have to stop taking the medication.
Possible food and drug interactions when taking Provera
If Provera is taken with certain other drugs, the effects of either
may be increased, decreased, or altered. It is especially important
to check with your doctor before combining Provera with aminoglutethimide
(Cytadren).
Special information if you are pregnant or breastfeeding
You should not take Provera during pregnancy. If you are pregnant
or plan to become pregnant, inform your doctor immediately.
Provera appears in breast milk. If you are a new mother, you may need
to choose between taking Provera and breastfeeding your baby.
Recommended dosage for Provera
